Definitely not advisable nor worth considering. It also would not be supported by Hortonworks support license.
The minimum cluster size for a production environment is typically seen as 3 management nodes that hold master services like namenode, zookeepers, etc + 4 data nodes that hold data in hdfs and also slave services.
The sandbox is a single node with everything, great for installing quickly, learning skills and perhaps doing simple demos ... but not production high availability, throughput, processing etc
See this post for a discussion of minimal deployment: https://community.hortonworks.com/questions/48572/physical-layout-of-architecture.html